Association of daytime napping with incidence of chronic kidney disease and end-stage kidney disease: A prospective observational study

Li, Qinjun1,2; Shan, Ying1,3; Liao, Jingchi4; Wang, Ling1,2; Wei, Yanling1,3; Dai, Liang1,3; Kan, Sen1,2; Shi, Jianqing4,5; Huang, Xiaoyan1,3; Lu, Guoyuan1

2024-03-21

10.1371/journal.pone.0298375

PLOS ONE   影响因子和分区

1932-6203

Background and aims Few studies have examined the relationship between daytime napping and risk of kidney diseases. We aimed to investigate the association of daytime napping with the incidence of chronic kidney disease (CKD) and end-stage kidney disease (ESKD). We also examined whether sleep duration modified the association of nap with CKD or ESKD.Methods We recruited 460,571 European middle- to older-aged adults without prior CKD or ESKD between March 13, 2006, and October 1, 2010, in the UK Biobank. Sleep behavior data were obtained through questionnaires administered during recruitment. The analysis of the relationship between napping and the occurrence of CKD and ESKD utilized Cox proportional hazards regression models. The modification role of sleep duration on the effect of nap on CKD and ESKD was also examined.Results After a mean follow-up of 11.1 (standard deviation 2.2) years, we observed 28,330 incident CKD cases and 927 ESKD cases. The daytime napping was associated with incident CKD (P for trend = .004). After fully adjusted, when compared with participants who did not take nap, those in sometimes and usually nap groups had higher risk of CKD. Nevertheless, the available evidence did not support a link between daytime napping and ESKD (P for trend = .06). Simultaneously, there was insufficient evidence suggesting that sleeping duration modified the association of daytime napping with incident CKD or ESKD.Conclusion Daytime napping was associated with an increased risk of CKD. However, the absence of conclusive evidence did not indicate a connection between daytime napping and ESKD.

SCI

英语

其他

National Natural Science Foundation of China[82204148] ; Shenzhen Science and Technology Innovation Commission Scientific Research Fund Projects["JCYJ20220531094401003","JCYJ20190809111017163"] ; Shenzhen's Sanming Project[SZSM201612061] ; Scientific Research Foundation of Peking University Shenzhen Hospital[KYQD2022203]

Science & Technology - Other Topics

Multidisciplinary Sciences

WOS:001190798400120

PUBLIC LIBRARY SCIENCE

Web of Science

1.Soochow Univ, Affiliated Hosp 1, Dept Nephrol, Suzhou, Jiangsu, Peoples R China
2.Xuzhou Med Univ, Affiliated Xuzhou Municipal Hosp, Dept Nephrol, Xuzhou, Jiangsu, Peoples R China
3.Peking Univ, Shenzhen Hosp, Dept Clin Res Acad, Renal Div, Shenzhen, Guangdong, Peoples R China
4.Southern Univ Sci & Technol, Dept Stat & Data Sci, Shenzhen, Guangdong, Peoples R China
5.Natl Ctr Appl Math, Dept Stat & Data Sci, Shenzhen, Guangdong, Peoples R China

Li, Qinjun,Shan, Ying,Liao, Jingchi,et al. Association of daytime napping with incidence of chronic kidney disease and end-stage kidney disease: A prospective observational study[J]. PLOS ONE,2024,19(3).

Li, Qinjun.,Shan, Ying.,Liao, Jingchi.,Wang, Ling.,Wei, Yanling.,...&Lu, Guoyuan.(2024).Association of daytime napping with incidence of chronic kidney disease and end-stage kidney disease: A prospective observational study.PLOS ONE,19(3).

Li, Qinjun,et al."Association of daytime napping with incidence of chronic kidney disease and end-stage kidney disease: A prospective observational study".PLOS ONE 19.3(2024).