| 题名 | High Performance, Multiplexed Lung Cancer Biomarker Detection on a Plasmonic Gold Chip |
| 作者 | |
| 通讯作者 | Lou, Jiatao; Qian, Kun |
| 发表日期 | 2016-11-22
|
| DOI | |
| 发表期刊 | |
| ISSN | 1616-301X
|
| EISSN | 1616-3028
|
| 卷号 | 26期号:44页码:7994-8002 |
| 摘要 | Diagnosis of lung cancer is performed using a plasmonic gold (pGOLD) chip through multiplexed near-infrared (NIR) detection of carcino-embryonic antigen (CEA), Cyfra21-1, and neuron-specific enolase (NSE) in the serum samples of patients. With approximate to 50-fold enhancement of NIR fluorescence, multiplexed microarray analysis of CEA, Cyfra21-1, and NSE in 10 mu L of human serum or whole blood samples on pGOLD chip leads to markedly improved limit-of-quantification, limit-of-detection, reproducibility, and higher diagnostic sensitivity and specificity compared to traditional biochips and Luminex technology currently in use in hospitals. |
| 相关链接 | [来源记录] |
| 收录类别 | |
| 语种 | 英语
|
| 重要成果 | NI期刊
; NI论文
|
| 学校署名 | 其他
|
| 资助项目 | Shenzhen program[KQTD20140630160825828]
|
| WOS研究方向 | Chemistry
; Science & Technology - Other Topics
; Materials Science
; Physics
|
| WOS类目 | Chemistry, Multidisciplinary
; Chemistry, Physical
; Nanoscience & Nanotechnology
; Materials Science, Multidisciplinary
; Physics, Applied
; Physics, Condensed Matter
|
| WOS记录号 | WOS:000388171100006
|
| 出版者 | |
| EI入藏号 | 20164002866885
|
| EI主题词 | Biochips
; Biological Organs
; Body Fluids
; Diagnosis
; Diseases
; Gold
; Infrared Devices
; Microarrays
; Plasma Diagnostics
; Plasmonics
; Plasmons
|
| EI分类号 | Bioengineering And Biology:461
; Precious Metals:547.1
; Plasma Physics:932.3
|
| ESI学科分类 | MATERIALS SCIENCE
|
| 来源库 | Web of Science
|
| 引用统计 |
被引频次[WOS]：86
|
| 成果类型 | 期刊论文 |
| 条目标识符 | //www.snoollab.com/handle/2SGJ60CL/29365 |
| 专题 | 工学院_材料科学与工程系 |
| 作者单位 | 1.Shanghai Jiao Tong Univ, Shanghai Chest Hosp, Sch Biomed Engn, Shanghai 200030, Peoples R China 2.Shanghai Jiao Tong Univ, Med X Res Inst, Shanghai 200030, Peoples R China 3.Stanford Univ, Dept Chem, Stanford, CA 94305 USA 4.South Univ Sci & Technol China, Dept Mat Sci & Engn, Shenzhen 518055, Peoples R China 5.Tsinghua Univ Shenzhen, Res Inst, Res Ctr Adv Mat & Biotechnol, Shenzhen 518057, Peoples R China |
| 推荐引用方式 GB/T 7714 |
Liu, Bin,Li, Yaling,Wan, Hao,et al. High Performance, Multiplexed Lung Cancer Biomarker Detection on a Plasmonic Gold Chip[J]. ADVANCED FUNCTIONAL MATERIALS,2016,26(44):7994-8002.
|
| APA |
Liu, Bin.,Li, Yaling.,Wan, Hao.,Wang, Lin.,Xu, Wei.,...&Qian, Kun.(2016).High Performance, Multiplexed Lung Cancer Biomarker Detection on a Plasmonic Gold Chip.ADVANCED FUNCTIONAL MATERIALS,26(44),7994-8002.
|
| MLA |
Liu, Bin,et al."High Performance, Multiplexed Lung Cancer Biomarker Detection on a Plasmonic Gold Chip".ADVANCED FUNCTIONAL MATERIALS 26.44(2016):7994-8002.
|
| 条目包含的文件 | ||||||
| 文件名称/大小 | 文献类型 | 版本类型 | 开放类型 | 使用许可 | 操作 | |
| liu2016.pdf（1171KB） | -- | -- | 限制开放 | -- | ||
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